Answer:
Sure! Visit the Mayor's Community Assistance Unit for information. In general, you must make application with your local Community Board (list of Brooklyn Community boards); Block party applications must be submitted no less than 60 days before the event, and you'll also probably need some other permits such as a permit for amplified sound (from your local police precinct), a permit for food sales from the Department of Health, a permit to sell merchandise from the Department of Consumer Affairs, etc.
Best place to start is the Community Assistance Unit link above.
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